Recent Representative publications include: Lucie JelÃnková, Yevel Flores-Garcia, Sarah Shapiro, Bryce Roberts, Nikolai Petrovsky, Fidel Zavala, & Bryce Chackerian (2022). Bryce Roberts (Research Scientist), Medical Student at UNM School of Medicine.Javier Leo (Research Technician), Graduate Student at MD Anderson Cancer Center/UT Health.Rabia Khan (MS student), Intern at Sandia National Laboratory.Temi Ajayi (Research Technician), Medical student at UNM School of Medicine.Ashvini Vaidya (MS student and research scientist), Medical student at Emory University.Alexandra Fowler (PhD student), Post-doctoral fellow at Merck Alemu Mogus (Post-doctoral fellow), Post-doctoral fellow, University of Virginia Naomi Lee (Post-doctoral fellow), Assistant Professor, Northern Arizona University Susan Core (Sr Research Specialist), Research Specialist, Frietze Laboratory, UNM.Kathryn Frietze (Post-doctoral fellow/Research Assistant Professor), Assistant Professor, UNM School of Medicine Ebenezer Tumban (Post-doctoral fellow/Research scientist), Associate Professor, Texas Tech University (Amarillo) Erin Crossey (MD/PhD student), Pulmonary Fellowship Program, Boston University Mitchell Tyler (PhD student), Senior Analyst, National Center for Medical Intelligence Jayne Christen (Post-doctoral fellow), Health Science Administrator, NCI/NIH John O'Rourke (Research Assistant Professor), Director of Assay Development, BennuBio Inc. Alex Medford (MS student), Scientist, Colorado Department of Health.Paul Durfee (Research Technician), Associate Director of Formulation and Delivery, Laronde Brett Manifold-Wheeler (Research Technician), Lecturer, UNM Dept. Marisa Rangel Durfee (Research Technician), Grants Program Manager at Circumvent Pharamaceuticals.Zoe Hunter (PhD student), Senior Manager, Publications at Pharmacyclics, an AbbVie company Lucie Jelinkova (Post-doctoral Research Scientist) Jeffrey Michael Gorvetzian Endowed Professor of Biomedical Research Excellence STC.UNM (Science and Technology Center at UNM) Innovation Fellow, 2017 Biomedical Sciences Graduate Program Outstanding Mentor Award, 2019 Fellow of the National Academy of Inventors, 2019Ĭhackerian Lab (October 2019) Lab Members: We are funded by multiple grants from the National Institutes of Health To learn more about our work, follow us on Twitter & Awards Using virus-like particles derived from RNA bacteriophage, the Chackerian lab has collaborated with David Peabody to develop a variety of tools for vaccine production and to implement a system that allows vaccines to be rapidly identified by affinity selection.Ĭurrently, the Chackerian laboratory has projects to develop novel vaccines targeting diverse pathogens (including malaria, Neisseria gonorrhoeae, Sin Nombre virus, and SARS-CoV-2) and vaccines for chronic disease (including dyslipidemia, Alzheimer's, and migraines). This ability to enhance immunogenicity does not only apply to epitopes derived from traditional targets, such as pathogens, but also to self-antigens which are normally subject to the mechanisms of B cell tolerance. Our lab has demonstrated that antigens that are normally poorly immunogenic can be made highly immunogenic by displaying them in a multivalent, repetitive format on the surface of virus particles essentially using viruses as scaffolds to produce novel vaccines. It has long been recognized that highly dense repetitive antigens such as virus particles induce strong immune responses.
The Chackerian laboratory is interested in vaccine development particularly the use of virus particles as platforms for antigen display.
0 kommentar(er)
